PHC230H1

Pharmaceutics 1

This course introduces the key concepts in the design, manufacture, and use of efficacious dosage forms. The characteristics of different delivery routes are discussed. The course focuses on the role of pharmaceutics in drug development, and the role of anatomy and physiology in the conception and design of effective dosage forms. Topics covered include biopharmaceutical considerations, pharmaceutical solutions, sterilization theories and techniques, complexation and solubility enhancement, pre-formulation, colloids and dispersions, powders and micromeritics, and solid-state properties. Students will gain an appreciation of how the properties of drug components (such as pH, salt concentration, co-solvents, sterility, colloids, dispersions, powders, and solids) determine the stability, solubility, and efficacy of drug products.