BIO477H5

The Human Genome and Cancer Biology

The first part of the course examines the structure and molecular biology of the human genome. Topics will include: the sequencing of the human genome; variation between genomes; and various aspects of functional genomics such as a brief overview of how gene expression is regulated and how genomics is being utilized in health and medicine. Techniques such as high throughput sequencing will be covered. The second part of the course examines the molecular and genetic basis of cancer including the role of oncogenes, tumor suppressor genes and cell cycle regulating proteins in the development of this disease. It also looks at cancer from a functional genomics perspective. Lectures and seminars involve presentations and discussion of recently published research articles.