BCH450H1

Antibiotics and Antibiotic Targets

This course will cover the action of the biochemical targets of the existing antibiotics (nucleotide-, RNA-, DNA-, protein- and cell wall synthesis, the manner in which these pathways are inhibited in antimicrobial therapy and the biochemical basis of antibiotic resistance. The biochemistry and origin of naturally occurring and synthetic antibiotics will be introduced. (Enrolment limited.)