BCH446H1

Membrane Dynamics of the Cell Surface

This course covers the principles and concepts related to molecular cell biology of the cell surface in multicellular organisms. Topics include: biophysical properties of cells, membranes, and extracellular matrix, dynamic remodelling of the cytoskeleton; cell-cell and cell-matrix interactions; maintenance of planar and apical-basal cell polarity; cytokinesis, viral uptake by macropinocytosis and engulfment by phagocytosis. In addition to lectures, groups of students will interpret a recent scientific paper related to the course material to be formally presented during regular class hours.